When I said spiders were a special case, I was informed that spiders of unknown "poisonous" capacity are considered wild and should not be approached. Since it's actually rather difficult to tell if a spider is poisonous, one would naturally assume all spiders are to be feared. Since this implies you need to live in a bubble to achieve a spiderless-world, I'm going to devise a test. If you look at a spider and say "spider spider, go and hider" and the spider runs, or just sits perfectly still, it's harmless. However, if it approaches, you should consider crushing it. :)
Of course, given the wide range of possibilities, I just want to teach Ralphie the Roach to sit up, shake hands and roll over :-P